The Role of Corticosteroids in the Treatment of Metastatic Epidural Spinal Cord Compression

نویسنده

  • Lisa M Ruppert
چکیده

Copyright: © 2013 Ruppert LM. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Metastatic epidural spinal cord compression is the third most common cause of adult compressive myelopathy, after acute trauma and degenerative etiologies. In individuals with systemic cancer it is one of the most common neurologic complications, following the brain parenchymal metastases [1]. Epidural spinal cord compression can be caused by metastases from most primary malignancies. Solid tumors of the lung, breast, prostate and kidney, lymphoma and sarcoma, however, have a higher predisposition for spinal metastases [2].

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Metastatic Epidural Spinal Cord Compression American College of Radiology ACR Appropriateness Criteria METASTATIC EPIDURAL SPINAL CORD COMPRESSION AND RECURRENT SPINAL METASTASIS Expert Panel on Radiation Oncology–Bone Metastases: Simon Shek-Man

Metastatic Epidural Spinal Cord Compression The axial skeleton is a commonly involved site in patients with bone metastases. Progressive spinal metastasis may result in epidural spinal cord compression, and lead to paresis and paralysis if left untreated [1-3]. The treatment of metastatic epidural spinal cord compression is determined by disease factors such as histology, site of disease, exten...

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1 Wright RL. Malignant tumors in the spinal extradural space: results of surgical treatment. Ann Surg 1963; 157:227–231 2 Gilbert RW, Kim JH, Posner JB. Epidural spinal cord compression from metastatic tumor: diagnosis and treatment. Ann Neurol 1978; 3:40–51 3 Sorensen PS, Borgesen SE, Rohde K, et al. Metastatic epidural spinal compression: results of treatment and survival. Cancer 1990; 65:150...

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تاریخ انتشار 2013